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In recent years, the scientific community has focused on two key endogenous molecules NAD (Nicotinamide Adenine Dinucleotide) and reduced glutathione (GSH) whose progressive depletion with age is now correlated with the main signs of cutaneous and systemic ageing. NAD: the anti-ageing metabolic powerhouse NAD is an essential coenzyme involved in hundreds of redox reactions and a fundamental substrate for sirtuins and PARPs, pro-longevity enzymes that regulate DNA repair and mitochondrial function

Then we evaluated the dendriplex PURE G4 -LA 12 -anti- GLS1 -siRNA effect directly on GBM cells and after crossing two in vitro models of the BBB

GSTs are also involved in the phase I detoxification process such as dehydrochlorination of 1,1,1-Trichloro-2,2-bis( p -chlorophenyl) ethane (DDT) to less toxic 1,l-Dichloro-2,2-bis( p -chlorophenyl) ethylene (DDE) [22, 43, 44]

Long-term assessment of post-treatment symptoms in patients with culture-confirmed early Lyme disease